Islet Biology Program

The Islet Biology Program includes research related to the development and function of the islet. One primary research focus is the overlapping steps in the progression from stem cells to organized islets. Investigators compare and contrast pancreas development in organisms as varied as flies, zebrafish, mice, and humans. There is a strong emphasis on studies of islet regeneration oriented towards producing islets for transplantation into patients with type 1 and type 2 diabetes. Islet Biology researchers also study islet function ranging from the generation of islet autoantigens predisposing islets to destruction in Type 1 diabetes to the regulation of beta-cell turnover and the progressive decline in beta cell function leading to beta cell failure and Type 2 diabetes

Islet Biology Program Members and Research Activities

Islet Differentiation and Function

 

Blelloch, Robert
Desai, Tejal
Ding, Scheng
German, Michael
Grodsky, Gerry
Hebrok, Matthias
Jan, Lily
Ku, Gregory
McManus, Michael
Oakes, Scott
Papa, Feroz
Reiter, Jeremy

CENTER MEMBERS ARE REMINDED TO ACKNOWLEDGE DERC CENTER GRANT (P30 DK063720) CONTRIBUTIONS WITH ‘THIS RESEARCH WAS SUPPORTED BY GRANTS X, Y FROM NIH P30 DK063720'.